Preparation H suppositories are perfect for anytime relief of internal hemorrhoids and are effective at shrinking swollen hemorrhoidal tissues while providing prompt soothing relief from pain, itching, and discomfort. Preparation H Suppositories includes the active ingredient Bio-Dyne, which is yeast as a live cell derivative. Regular application of Preparation H Suppositories provides continual therapy for relief of hemorrhoidal symptoms. This package includes 24 individual packets of Preparation H Suppositories. Insert one suppository in the morning, at night, after each bowel movement, and whenever symptoms occur.