Waffle outsole and flex grooves help keep you cushioned and stable. Run by your own rules in the Nike Run Defy. A foam midsole, breathable upper and reliable traction combine to make a shoe that's ready for runs of all lengths and paces. Mesh on the upper The mesh on the upper adds breathability. Foam midsole A foam midsole delivers a soft ride. Flex grooves Flex grooves create a cushioned effect for your run. Waffle outsole The Waffle outsole is a made from a durable, flexible material that helps keep you on the move.